Scientists talk about the consequences of smoking electronic cigarettes with replaceable cartridges

New studyEffects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice, conducted by a group of scientists from the University of California at San Diego School of Medicine, confirmed the extremely the negative impact of the systematic use of electronic cigarettes with replaceable capsules or cartridges (POD systems).

Extensive studies in mice have shown many elevated inflammatory markers in various organs, including the brain, heart, lungs and colon. Neuroinflammation was the most notable side effect.

This study was the first to thoroughly examine the impact of e-cigarettes based on removable media such as JUUL. Most of the previous work on the dangers of e-cigarettes has focused on older devices like so-called vape pens.

To study the effects of smoking over a long period of time, the researchers used aerosols of two flavors of JUUL - mint and mango. Animals were exposed to them for 20 minutes three times a day for 12 weeks.

Three months later, the most significant markers of inflammation were found in the brains of the animals. Increased signs of inflammation were concentrated in an area called the nucleus accumbens. It plays a role in behavior modification, including anxiety and depression.

Researchers Caution emphasizethat their study did not include tracking behavioral changes in animals, so At this stage, the impact of e-cigarette exposure on mental health is purely hypothetical.

However, the real surprise for the scientists was the discovery of differences in the expression of inflammatory genes between two different flavors of JUUL. Inflammatory patterns between flavors were particularly different in the colon and heart.

So, in mice that inhaled peppermint aerosols, the heart became more susceptible to bacterial pneumonia. Whereas in the case of mango, this effect was not observed.

The researchers suggest that this points to fundamental differences in the biological action of different chemical flavors. However, more specific conclusions require a much deeper study of the influence of these components.

Of course, exposing animals to e-cigarette aerosols for 20 minutes three times a day is not exactly the same as humans inhaling these fumes. Yes, and three months is not quite similar to the constant use of a person for several years. Scientists recognize this.

Still, these kinds of experiments help focus future research and provide insight into what kinds of negative effects to look out for in humans. Specifically in this case, the results show that the systematic use of electronic cigarettes with replacement cartridges can lead to inflammation in several different vital organs.