Where does the chronic fatigue and how to win

Constant fatigue - the bane of many. Kind and health care, and not to overexert, and even vitamins you drink, but I still feel like a fly in amber: so be covered himself with a blanket and did not look at anyone.

What is chronic fatigue

Causes fatigue may be in excess. For example, it is often prolonged psychological stress, sometimes - fatigue and associated emotional burnout.

As a rule, cheerfulness recipe in this case, it sounds nice and simple. Suffice it to catch up on sleep, go on vacation, take time to rest and hobbies - and bang, you're back in good spirits and full of energy. But simple recipes does not always work. And even if the holiday does not help, it is worth the alert.

If fatigue does not pass is not a week or two, but for months, then the problem is more serious than we would like.

In such cases, doctors say chronic fatigue syndrome (CFS). In the US alone suffer from itME / Chronic Fatigue Syndrome Awareness Day up to 2.5 million people. As a rule, the main symptom is a lack of power for three weeks or more. This is a key feature, but not the only one.

symptoms of chronic fatigue

In addition to always tired and categorical refusal to crawl out from under the blanket, even to where you really want, there are still at least a few signsChronic Fatigue Syndrome:

1. Problems with memory and concentration.
2. Frequent headaches or dizziness.
3. Insomnia, intermittent sleep or, alternatively, constant sleepiness.
4. Sore throat.
5. Discomfort in the muscles.

It's about you? Well, modern science has little understanding of what to do with you. The exact range of the causes of chronic fatigue has not yet disclosed, and therefore precise treatment protocols do not existChronic Fatigue Syndrome. Chronic fatigue is one of those disorders that doctors often try to correct right Nutrition, exercise, cognitive behavioral therapy and do not always achieve lasting benefits results.

But there is good news: In 2017, Australian doctors found that the syndrome is associated with certain defectsImpaired calcium mobilization in natural killer cells from chronic fatigue syndrome / myalgic encephalomyelitis patients is associated with transient receptor potential melastatin 3 ion channels cell receptors. This confirms the already not a new version of that chronic fatigue is a result of problems with the energy exchangeMetabolism in chronic fatigue syndrome in cells.

Among these energy problems can be identified the three most common:

1. The cells do not have enough food.
2. Cells can not give energy.
3. The cells do not have enough oxygen.

What if the cells do not have enough power

In normal cells work like this: from the blood in their power unit (mitochondria) received glucose, amino acids, fatty acids and other nutrients. Mitochondria - these small furnace they are burned (oxidized oxygen) Received food to carbon dioxide and water, and process produces energy - the same one that makes the cell able to function, and the body as a whole - to breathe, to move, think. But it happens that in the blood meal to eat, and the cell can not get it. And starving cells, tissues and organs declare themselves chronic fatigue.

What's happening

The reason may be, for example, in insulin resistanceSigns of Insulin Resistance. The hormone insulin - a kind of butler, informing the cell that dinner is served. To receive this information in the cells has special connectors - receptors. Insulin docks with a receptor (such as USB flash drive with a USB-port) sends a signal: "Food!" - and the cell includes a mechanism for injecting the nutrients inside. This is normal.

If the connector for some reason rusty (become resistant), insulin simply can not reach. In the blood, it becomes more and more outstanding in glucose and fatty acids are stored in the form of excess fat tissue - in general, begins to develop Type II diabetes. A cell is still hungry and feel more and more tired.

Alternatively, insulin resistance is all right, the food cell sees, but download a can. Because the decreased membrane permeabilityMembrane transportThrough which the food arrives. membrane permeability worsenMitochondrial Disease:

1. Viral infections.
2. Dehydration and / or prolonged fasting.
3. The intense heat or cold.
4. Paracetamol.
5. Some antidepressants.
6. Dishes with sodium glutamate (almost all of the processed products, which can be found on supermarket shelves).
7. Cigarette smoke.

How to fight it

Hand over the biochemical analysis of blood, checking glucose tolerance and a number of indicators, the fixing state of energy metabolism (eg, creatine kinase and its fractions). Discuss the results with the therapist.

Minimize harmful factors on time to stop unnecessarily rigid diet, adjust water regimeAbolish alcohol, quit smoking. Abandon paracetamol. Instead, it is better to take ibuprofen: it is saferIBUPROFEN VS PARACETAMOL).

What if the cells can not give energy

If insulin resistance and mitochondrial disorders - is that the cells do not get food in the right quantity, hypothyroidism - that the cell can not give energy as it should be.

What's happening

One reason for this - Faulty connector of another cell - receptor thyroid hormone. Thyroid hormone called T3 (triiodothyronine) from cells requires accumulated energy. But since the connector does not work properly, the cell can not hear, think that no one needs, and tired to sleep.

How to fight it

Tested for hormone T3 and the closely related T4, TSH, and seek the advice of an endocrinologist.

What if the cells do not have enough oxygen

The oxidative processes that occur in the mitochondria, oxygen appears. And much depends on it.

What's happening

If little oxygen, the cells are simply not able to effectively recycle the energy of the same glucose contained in the blood.

How to fight it

To breathe fresh air. And as much as possible. Walking at least one hour a day - and preferably in the park rather than city streets. Also be sure to regularly ventilate. Yes, hard to believe that in time the open window can get rid of chronic fatigue. But perhaps it is your option?

And as a bonus

Many people know how important for good health vitamins A, B, C, E... But vitamin D is often neglected. Meanwhile, it is this vitamin has been actively involved in the regulation ofVitamin D energy metabolism.

Vitamin molecules cling to perceive their receptors on the cell membrane, and the atoms necessary substances in the blood (in particular calcium), - per molecule exposed outward tail. Bundle of calcium to vitamin D and perceiving its receptor on the membrane acts as a kind of the magnetic core, and the whole chain of other essential elements and amino acids contained in the blood, together with this rod is pulled into cells. Of course, this is a very rough picture, and yet it's pretty accurately describes the process.

There is a shortage of Vitamin D - means constant fatigue possible. Talk about this with your therapist.

see also

• 4 reasons why we feel tired after waking →
• Fatigue affects decision-making and implementation of new habits →
• The law of equal forces: how to achieve their goals and not to feel fatigue →